Abstract: For the east center in Hongqiao transport hub, fluid-solid coupling FEM analysis of multi-grade dewatering is made based on the Biot's consolidation theory. Pumping tests are firstly simulated to determine soil parameters by means of the back analysis of displacement and pore pressure. Then a fluid-solid coupling model is established to analyze dewatering and excavation by use of the transient analysis method and the birth-death element method respectively. The impact on the environment and foundation pit system are analyzed at the same time. Through the comparison between the calculated and measured values, the transient analysis method in fluid-structure coupling analysis is proved to be correct and feasible.