Abstract: A super element method used to analyze the interaction of a space multistory frame structure grillage foundation beams on elastic foundation is presented. The space multistory frame structure and grillage foundation beams are treated as grillage shear bending beams, and are divided into super element according to the columns span. Then, the interaction problems of the shear bending beams on various elastic foundation are analyzed by finite element. The method presented in this paper is simpler in calculation and can be used more widely.